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Consistently, genetically predicted acetyl-carnitine was also related to higher risk of CAD (OR 1.06, 95% CI 1.01 to 1.10) and heart failure (OR 1.07, 95% CI 1.01 to 1.14) (Additional file 2: Fig

Metabotropic glutamate receptors are composed of mGluR18 subunits and have seven transmembrane segments that are connected to heterotrimeric G proteins